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Nivolumab, sold under the brand name Opdivo, is an anti-cancer medication in the class of immune checkpoint inhibitors. It selectively binds and blocks the programmed death-1 (PD-1) receptor on T cells, thereby facilitating their activation. 15 juin 2025 · Nivolumab is a medicine that may treat certain cancers by working with your immune system. Nivolumab can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. Nivolumab works by binding to and blocking the protein PD-1 on the surface of some cancer cells, which keeps cancer cells from suppressing the immune system. This allows the immune system to attack the cancer cells. Nivolumab is a type of immunotherapy drug called an immune checkpoint inhibitor. 1 juin 2025 · Nivolumab injection is used alone or together with other medicines (eg, ipilimumab) to treat melanoma (skin cancer) that has spread throughout the body (metastatic) or that cannot be removed by surgery. OPDIVO ® (nivolumab) is a prescription medicine used in combination with YERVOY ® (ipilimumab) to treat adults with a type of liver cancer called hepatocellular carcinoma (HCC) when your liver cancer cannot be removed by surgery or has spread, and you have received prior treatment with sorafenib. Nivolumab is a type of targeted therapy that does not directly kill cancer cells, but targets and alters a specific cell mechanism that promotes cancer growth and spread. Nivolumab works by stimulating the body’s own immune system to fight against cancer cells. It is a monoclonal antibody. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. What should I tell my care team before I take this medication? This medication is infused into a vein. It is given in a hospital or clinic setting. Nivolumab is used to treat melanoma, non-small cell lung cancer, kidney cancer, Hodgkin lymphoma, mesothelioma, bladder cancer, oesophageal
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